Trade name: EntrestoSponsor: NOVARTISTherop-Cat: heart failureIndication: reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction.Chemical name of Sacubitril:4-{[(2S,4R)-1-(4-Biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoic acidCAS#149709-62-6Chemical structure:Intermediates of […]
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Therop-Cat: Cytotoxic linear peptide Indication: anti-cancer CAS#: 52659-57-1 Chemical structure: Intermediates of Aplysiatoxin/Dolastoxin:CAS#37577-28-9 : (1S,2R)-(+)-2-AMINO-1-PHENYL-1-PROPANOLChemical structure:2. CAS#120205-48-3 : 2-Methyl-2-propanyl (3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino) heptanoate hydrochloride (1:1)Chemical structure:3. CAS#120205-50-7 : ((2R,3R)-3-((S)-1-(tertbutoxycarbonyl)pyrrolidin-2-yl)-3-Methoxy-2-Methylpropanoic acidChemical structure: Add: 7-3-601, Zuoanmingdi, Xianshuigu,Jinnan District, Tianjin 300350 ChinaTel&Fax: […]
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Tedizolid Phosphate（formerly torezolid）Trade name: SivextroSponsor: CUBIST PHARMACEUTICALSTherop-Cat: an oxazolidinone-class antibioticIndication: acute bacterial skin and skin structure infections (ABSSSI)Chemical name: [(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphateCAS# 856867-55-5Chemical structure: TedizolidCAS#856866-72-3Chemical name: (R)-3-(3-fluoro-4-(6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxyMethyl)oxazolidin-2-oneChemical structure: Intermediates of TedizolidCAS#444335-16-4 : (5R)-3-(4-broMo-3-fluorophenyl)-5-(hydroxyMethyl)-1,3-oxazolidin-2-oneChemical structure: 2. CAS#1056039-83-8 : 2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridineChemical […]
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Trade name: HetliozSponsor: VANDA PHARMACEUTICALSTherop-Cat: melatonin receptor agonistIndication: N24HSWD (non-24-hour sleep–wake disorder)Chemical name: (1R-trans)-N-[[2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamideCAS# 609799-22-6Chemical structure:Intermediate of Tasimelteon:CAS#230642-84-9 ：4-ethenyl-2,3-dihydrobenzofuran Add: 7-3-601, Zuoanmingdi, Xianshuigu,Jinnan District, Tianjin 300350 ChinaTel&Fax: +86-22-28567687Mobile: +86-15620196887Email: sales@reliablepharmatech.com
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Trade name: AlecensaSponsor: Chugai Pharmaceutical(Roche)Therop-Cat: anti-cancerIndication: ALK & NSCLCChemical name: 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrileCAS# 1256580-46-7Chemical structure: Intermediates of Alectinib:CAS# 1256578-99-0 : 6-bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one2. CAS# 4133-34-0: 3,4-Dihydro-7-methoxy-2(1H)-naphthalenone3. CAS# 1256579-06-2: 9-Bromo-8-hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile4. CAS# 17672-26-3: 3-hydrazinylbenzonitrile Add: 7-3-601, Zuoanmingdi, Xianshuigu,Jinnan District, Tianjin 300350 ChinaTel&Fax: +86-22-28567687Mobile: +86-15620196887Email: sales@reliablepharmatech.com
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Trade name: Axert, Almogran Sponsor: Almirall, S.A. Therop-Cat: anti-migraine Indication: heavy migraine headache Chemical name: 1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine CAS# 154323-57-6 Chemical Structure: Almotriptan MalateCAS#181183-52-8Intermediates of Almotriptan：CAS# 334981-11-2 : 4-(1-Pyrrolidinylsulfonylmethyl) phenyl hydrazine monohydrochloride mono hydrate2. CAS#54322-20-2: 4-chloro-1-hydroxy-1-butane sulfonate sodium3. […]
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Avibactam Sodium Trade name：AVYCAZ(Ceftazidime/avibactam sodium) Originator: Actavis (now Teva)& AstraZeneca Therop-Cat：antibactic, β-lactamase inhibitor Indication：cUTI, cIAI Chemical name：(2S,5R)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide monosodium salt CAS# 1192491-61-4 Chemical Structure： Intermediates of Avibactam Sodium: Avibactam: CAS#1192500-31-4: (2S,5R)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carbox amide Chemical […]
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LinezolidTrade name： ZYVOX， LINEZOLIDTherap-Cat: AntibioticIndication：infections caused by Gram-positive bacteria that are resistant to other antibioticsChemical name：(s)-n-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl]methyl]acetamideCAS#: 165800-03-3Chemical structure: Intermediates of Linezolid:CAS# 168828-82-8 : (5R)-(hydroxymethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]oxazolidin-2-onechemical structure: CAS# 174649-09-3:(R) – (3 – (3- fluoro-4- morpholinophenyl) – 2- oxo-5-oxazolidinyl) methyl methanesulfonate Add: 7-3-601, […]
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PosaconazoleCAS#: 171228-49-2Chemical name：4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-oneChemical structure:Major intermediates:CAS# 175712-02-4: (5R-cis)- p-Chlorobenzenesulfonic acid 5-(2,4-difluoro- phenyl)-5-[1,2,4]triazol-1-ylmethyl-tetrahydro-furan-3-ylmethyl ester Chemical structure:CAS#149809-43-8: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol -1-ylmethyl-tetrahydro-furan-3-ylmethyl esterChemical structure: CAS# 74853-08-0: 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Chemical structure:CAS# 184177-81-9 : phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate Chemical structure:CAS# 170985-85-0 :((2S,3S)-2-(benzyloxy)pentan-3-yl)hydrazinecarboxaldehyde Chemical structure:CAS# 183871-36-5 : ((2S,3S)-2-(benzyloxy)pentan-3-yl)hydrazine […]
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