Posaconazole

Posaconazole

CAS#: 171228-49-2

Chemical name:4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

Chemical structure:posaconazole structure

Major intermediates:
CAS# 175712-02-4: (5R-cis)- p-Chlorobenzenesulfonic acid 5-(2,4-difluoro-
phenyl)-5-[1,2,4]triazol-1-ylmethyl-tetrahydro-furan-3-ylmethyl ester
Chemical structure:

posaconazole intermediate 1

CAS#149809-43-8: (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol -1-ylmethyl-tetrahydro-furan-3-ylmethyl ester

Chemical structure: 

posaconazole intermediate 149809-43-8

CAS# 74853-08-0: 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
Chemical structure:

posaconazole intermediate 2-2-1

CAS# 184177-81-9 : phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate
Chemical structure:

posaconazole intermediate 2-2

CAS# 170985-85-0 :((2S,3S)-2-(benzyloxy)pentan-3-yl)hydrazinecarboxaldehyde
Chemical structure:

posaconazole intermediate 2-1

CAS# 183871-36-5 : ((2S,3S)-2-(benzyloxy)pentan-3-yl)hydrazine dibenzoyl-D-tartrate
Chemical structure:

posaconazole intermediate 2-1-1

CAS# 184177-83-1 : 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one
Chemical structure:

posaconazole intermediate 2

For other intermediates not listed here, please contact us for detailed information.

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Posted in Antifungal and tagged , .