Intermediates of Telaprevir

Telaprevir

Brand name: Incivek and Incivo

Developed by: Vertex Pharmaceuticals and Johnson & Johnson

Therop-Cat: anti-viral (protease inhibitors)

Indication: hepatitis C

Chemical name: (1S,3aR,6aS)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-1-carboxamide

CAS#402957-28-2

Chemical structure:

402957-28-2

Intermediates of Telaprevir:

1. CAS#87269-87-2:(1S,3S,5S)-2-Azabicyclo[3,3,0]octane-3-carborylic acid benzyl ester hydrochloride

telaprevir intermediate

2. CAS#1147103-42-1: (1S,3aR,6aS)-Octahydrocyclopenta[c]pyrrole-1-carboxylic acid ethyl ester hydrochloride

 Telaprevir

3. CAS#402958-96-7: (2S)-2-Cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-Methyl-L-valine

Telaprevir intermediate

4. CAS#850252-34-5: (3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride

Telaprevir intermediate

5. CAS#14691-89-5: 4-acetamido tempo

4-acetamido tempo

 

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Posted in Antiviral and tagged , , .