Monthly Archives: November 2017

chemical structure of Ivabradine

Ivabradine

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Trade name: Corlanor (USA) Originator: Amgen and Servier Therop-Cat: cardiovascular Indication: heart-related chest pain and heart failure Chemical name: 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one CAS#155974-00-8 Chemical structure: During its development, ivabradine was known as S-16257. Intermediates of Ivabradine: 1. 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one Cas […]

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chemical structure of Alogliptin

Alogliptin

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Trade name: Nesina, Vipidia Originator: Takeda Therap-Cat: Anti-diabetic Indication：Type 2 diabetes Chemical name：2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl}methyl)benzonitrile CAS#: 850649-62-6 Chemical structure: Intermediates of Alogliptin: 4318-56-3 849217-48-7 188111-79-7 334618-23-4 865758-96-9 22115-41-9 Add: 7-3-601, Zuoanmingdi, Xianshuigu,Jinnan District, Tianjin 300350 ChinaTel&Fax: +86-22-28567687Mobile: +86-15620196887Email: sales@reliablepharmatech.com

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chemical structure of afatinib

Afatinib

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Trade name： Giotrif Therap-Cat: Anticancer Originator: Boehringer Ingelheim Indication：the first-line treatment of patients with distinct types of metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC) Chemical name：N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2-butenamide CAS#: 850140-72-6 Chemical structure: Intermediates of Afatinib: 162012-67-1 86087‐23‐2 314771-76-1 […]

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chemical structure of sitagliptin

Sitagliptin

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Sitagliptin Trade name： Januvia Therap-Cat: Antidiabetic Originator:  Merck & Co. Indication：diabetes mellitus type 2 First approved by USFDA in 2006 Chemical name：(R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine CAS#: 486460-32-6 Chemical structure: Intermediates of Sitagliptin: CAS# 486460-00-8 Chemical name: (3R)-3-(1,1-dimethylethoxy carbonyl)amino-4-(2,4,5-trifluorophenyl)butanoic acid Chemical structure: […]

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